Methylene blue as an antioxidant agent in experimentally-induced injury in rat liver
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چکیده
منابع مشابه
Methylene blue-induced phototoxicity: an unrecognized complication.
OBJECTIVE To describe photosensitization after prenatal exposure to a toxic amount of methylene blue and to alert pediatricians that, in a review of the literature, photosensitization (which this dye is capable of) has not been reported as a complication of prenatal exposure. DESIGN AND PATIENTS A descriptive report of physical findings and significant laboratory tests in a very low birth wei...
متن کاملBetaine as a methyl donor and an antioxidant agent in levodopa-induced hyperhomocysteinemia and oxidative stress in rat's kidney
BACKGROUND: Betaine has been shown to be antioxidantand methyl donor effects in our recent studies. OBJECTIVES: Inthe present study, the antioxidant and methyl donor properties ofbetaine in levodopa/benserazide-mediated hyperhomocysteinemiaand levodopa-induced oxidative stress in rat's kidney wereexamined. METHODS: Sprague-Dawley male rats were dividedinto levodopa (LD), Betaine (Bet.), levodop...
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Proveblue (international patent PCT/FR/2007/001193), which is a methylene blue preparation that complies with the European Pharmacopoeia and contains limited organic impurities and heavy metals of recognized toxicity, has previously been demonstrated to possess in vitro antimalarial activity (at a geometric mean 50% inhibitory concentration [IC50] of 3.62 nM) against 23 Plasmodium falciparum st...
متن کاملProtective Effect of Folic Acid against Apoptosis Induced by Ischemia/Reperfusion Injury in Rat Liver
The anti-apoptotic gene bcl-2 is located in mitochondria, but it is uncertain whether its expression affects hepatocyte survival in ischemia/reperfusion (I/R) injury. This experiment was designed to evaluate the role of folic acid in expression of bcl-2 in I/R in rat liver. Eighteen Wister rats were divided into sham-operated controlgroup (C) (n=6), I/R group (...
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ژورنال
عنوان ژورنال: Bratislava Medical Journal
سال: 2015
ISSN: 1336-0345
DOI: 10.4149/bll_2015_032